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Drospirenone

Cat. No.:YN481778

  • CAS No. :67392-87-4

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    • 产品名称: Drospirenone
      CAS No.: 67392-87-4
      Chemical Name: 1,3',4',6R,7R,8R,9S,10R,11,12,13S,14S,15S,16S,20,21-hexadecahydro-10,13-dimethyl-spiro[17H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-17,2'S(5'H)-furan]-3,5'(2H)-dione
      Synonyms:Dihydrospirorenone
      分子量:366.49
      分子式:C₂₄H₃₀O₃
      SMILES:C[C@@]12[C@](OC3=O)(CC3)[C@@H](C4)[C@@H]4[C@@]1([H])[C@@]([C@@H]5[C@H]6C5)([H])[C@]([C@](C6=CC7=O)(CC7)C)([H])CC2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Drospirenone(Dihydrospirorenone)是合成的孕酮,是spironolactone的类似物。
      IC50和靶点:
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    • Pollow, K., Juchem, M., Elger, W., et al.Dihydrospirorenone (ZK30595): A novel synthetic progestagen - characterization of binding to different receptor proteinsContraception46(6),561-574(1992)

      Muhn, P., Fuhrmann, U., Fritzemeier, K.-H., et al.Drospirenone: A novel progestogen with antimineralocorticoid and antiandrogenic activityAnn. N. Y. Acad. Sci.761(1),311-335(1995)

      Apter, D., Zimmerman, Y., Beekman, L., et al.Bleeding pattern and cycle control with estetrol-containing combined oral contraceptives: Results from a phase II, randomised, dose-finding study (FIESTA)Contraception94(4),366-373(2016)

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