Asoprisnil
Cat. No.:YN480706
| 产品名称: | Asoprisnil |
| CAS No.: | 199396-76-4 |
| Chemical Name: | [C(E)]-4-[(11β,17β)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4,9-dien-11-yl]-benzaldehyde, 1-oxime |
| Synonyms: | J867 |
| 分子量: | 449.58 |
| 分子式: | C₂₈H₃₅NO₄ |
| SMILES: | C[C@@]12[C@@](OC)(CC[C@]1([C@@]3(CCC4=CC(CCC4=C3[C@H](C2)C5=CC=C(C=C5)/C=N/O)=O)[H])[H])COC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Asoprisnil (J867) 是一种选择性孕激素受体 (progesterone receptor) 调节剂,对动物和人类中各种孕酮靶向组织具有混合的孕酮激动剂和拮抗剂作用。 |
| IC50和靶点: | |
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Schubert, G., Elger, W., Kaufmann, G., et al.Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11β-benzaldoxime substituted selective progesterone receptor modulators (SPRMs)Semin. Reprod. Med.23(1),58-73(2005)
DeManno, D., Elger, W., Garg, R., et al.Asoprisnil (J867): A selective progesterone receptor modulator for gynecological therapySteroids68(10-13),1019-1032(2003)