BMS-P5 free base
Cat. No.：YN310243
CAS No. ：1550371-22-6
| 产品名称: | BMS-P5 free base |
| CAS No.: | 1550371-22-6 |
| Chemical Name: | [(2S,5R)-5-amino-2-methyl-1-piperidinyl][2-[1-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methyl-1H-methanone |
| Synonyms: | |
| 分子量: | 472.58 |
| 分子式: | C₂₇H₃₂N₆O₂ |
| SMILES: | O=C(N1[C@@H](C)CC[C@@H](N)C1)C2=CC(OC)=C3C(N=C(C4=CC5=CC=CN=C5N4CC6CC6)N3C)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BMS-P5 free base 是特异性的、具有口服活性的肽精氨酸二亚胺酶 4(PAD4)的抑制剂。BMS-P5 free base 可阻断多发性骨髓瘤诱导的 NET 形成，并延缓肿瘤进程。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Li, M., Lin, C., Deng, H., et al.A novel peptidylarginine deiminase 4 (PAD4) inhibitor BMS-P5 blocks formation of neutrophil extracellular traps and delays progression of multiple myelomaMol. Cancer Ther.19(7),1530-1538(2020)
