Dynarrestin
Cat. No.：YN450050
CAS No. ：2222768-84-3
规格
价格(RMB)
库存
| 产品名称: | Dynarrestin |
| CAS No.: | 2222768-84-3 |
| Chemical Name: | 4-[4-(diethylamino)phenyl]-2-[(2,4-difluorophenyl)amino]-5-thiazolecarboxylic acid, ethyl ester |
| Synonyms: | |
| 分子量: | 431.50 |
| 分子式: | C₂₂H₂₃F₂N₃O₂S |
| SMILES: | O=C(C1=C(C2=CC=C(N(CC)CC)C=C2)N=C(NC3=CC=C(F)C=C3F)S1)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dynarrestin 是细胞质动力蛋白 1 和 2的氨基噻唑抑制剂。Dynarrestin 快速可逆地抑制动力蛋白 1 驱动的微管在体外滑动和细胞内动力蛋白 1 和 2 依赖性过程，而不影响 ATP 水解和干扰纤毛发生。Dynarrestin 抑制神经元前体和肿瘤细胞的刺猬因子 (Hh) 依赖性增殖。 |
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| Solvent & Solubility: |
Höing, S., Yeh, T.-Y., Baumann, M., et al.Dynarrestin, a novel inhibitor of cytoplasmic dyneinCell Chem. Biol.25(4),357-369(2018)
