RI-2
Cat. No.：YN290407
CAS No. ：1417162-36-7
| 产品名称: | RI-2 |
| CAS No.: | 1417162-36-7 |
| Chemical Name: | 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
| Synonyms: | RI2,RI 2 |
| 分子量: | 433.28 |
| 分子式: | C₂₁H₁₈Cl₂N₂O₄ |
| SMILES: | O=C(C(C1=CC=C(OC)C=C1)=C2N3CCOCC3)N(C4=CC=C(Cl)C(Cl)=C4)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RI-2 是一种可逆的RAD51抑制剂，IC50值为 44.17 μM，能够特异性地抑制人体细胞中的同源重组修复。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Budke, B., Kalin, J.H., Pawlowski, M., et al.An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivityJ. Med. Chem.56(1),254-263(2013)
