Remdesivir

Cat. No.：1809249-37-3

CAS No. ：1809249-37-3

产品名称:	Remdesivir
CAS No.:	1809249-37-3
Chemical Name:
Synonyms:	瑞德西韦; GS-5734
分子量:	602.58
分子式:	C₂₇H₃₅N₆O₈P
SMILES:	C[C@H](N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@](C#N)(C3=CC=C4C(N)=NC=NN43)[C@H](O)[C@@H]2O)=O)C(OCC(CC)CC)=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

Select Batch:

Purity: 0.98

Agostini, M.L., Andres, E.L., Sims, A.C., et al.Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonucleasemBio9(2),e00221-00218(2018)', 'Sheahan, T.P., Sims, A.C., Graham, R.L., et al.Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronavirusesSci. Transl. Med.9(396),eaal3653(2017)', 'Eastman, R.T., Roth, J.S., Brimacombe, K.R., et al.Remdesivir: A review of its discovery and development leading to emergency use authorization for treatment of COVID-19ACS Cent. Sci.6(5),672-683(2020)', 'Pruijssers, A.J., George, A.S., Schäfer, A., et al.Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in miceCell Rep.32(3),107940(2020)', 'Hu, W.-J., Chang, L., Yang, Y., et al.Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in miceActa Pharmacol. Sin.12,(2020)