Z-FA-FMK

Cat. No.：197855-65-5

CAS No. ：197855-65-5

产品名称:	Z-FA-FMK
CAS No.:	197855-65-5
Chemical Name:
Synonyms:	(1S)
分子量:	386.42
分子式:	C₂₁H₂₃FN₂O₄
SMILES:	O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(NC(C)C(CF)=O)=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Ahmed, N.K., Martin, L.A., Watts, L.M., et al.Peptidyl fluoromethyl ketones as inhibitors of cathepsin B. Implication for treatment of rheumatoid arthritisBiochem. Pharmacol.44(6),1201-1207(1992)', 'Lopez-Hernandez, F.J., Ortiz, M.A., Bayon, Y., et al.Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathwayMol. Cancer Ther.2(3),255-263(2003)', 'Harth, G., Andrews, N., Mills, A.A., et al.Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruziMol. Biochem. Parasitol.58(1),17-24(1993)', 'Lawrence, C.P., Kadioglu, A., Yang, A.L., et al.The cathepsin B inhibitor, z-FA-FMK, inhibits human T cell proliferation in vitro and modulates host response to pneumococcal infection in vivoJ. Immunol.177(6),3827-3836(2006)', 'Kim, M., Hansen, K.K., Davis, L., et al.Z-FA-FMK as a novel potent inhibitor of reovirus pathogenesis and oncolysis in vivoAntivir.Ther.15(6),897-905(2010)