Dihydrotanshinone I
Cat. No.：YN251478
CAS No. ：87205-99-0
| 产品名称: | Dihydrotanshinone I |
| CAS No.: | 87205-99-0 |
| Chemical Name: | (1R)-1,2-dihydro-1,6-dimethyl-phenanthro[1,2-b]furan-10,11-dione |
| Synonyms: | 二氢丹参酮 I |
| 分子量: | 278.30 |
| 分子式: | C₁₈H₁₄O₃ |
| SMILES: | O=C(C1=C2C=CC3=C1C=CC=C3C)C(C4=C2OC[C@@H]4C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dihydrotanshinone I 是从丹参中分离到的天然产物，广泛用于心血管疾病的研究。Dihydrotanshinone I 可抑制 MERS-CoV。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
D'Agostino, V.G., Lal, P., Mantelli, B., et al.Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional functionSci. Rep.5:16478,(2015)
Choi, H.S., and Kim, K.M.Tanshinones inhibit mast cell degranulation by interfering with IgE receptor-mediated tyrosine phosphorylation of PLCγ2 and MAPKPlanta Med.70(2),178-180(2004)
Park, J.W., Lee, S.H., Yang, M.K., et al.15,16-Dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilizationArch. Pharm. Res.31(1),47-53(2008)
Liu, J.J., Wu, H.H., Chen, T.H., et al.15,16-Dihydrotanshinone I from the functional food Salvia miltiorrhiza exhibits anticancer activity in human HL-60 leukemia cells: In vitro and in vivo studiesInt. J. Mol. Sci.16(8),19387-19400(2015)
Kim, D.H., Jeon, S.J., Jung, J.W., et al.Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in miceEur. J. Pharmacol.574(2-3),140-147(2007)
