DOV-216,303 Free Base
Cat. No.：YN380132
| 产品名称: | DOV-216,303 Free Base |
| CAS No.: | 66504-40-3 |
| Chemical Name: | |
| Synonyms: | DOV-216303 |
| 分子量: | 228.12 |
| 分子式: | C₁₁H₁₁Cl₂N |
| SMILES: | ClC1=C(Cl)C=C(C=C1)C12CC1CNC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DOV-216,303 (Free Base) 是有效的5-羟色胺、去甲肾上腺素、多巴胺再摄取的三重抑制剂，其对 hSERT、hNET 和 hDAT 的IC50值分别为 14 nM，20 nM和78 nM。在嗅球切除大鼠模型中，可增加前额皮质中单胺的释放及具有抗抑郁的作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
