3-AP
Cat. No.：YN290016
CAS No. ：143621-35-6
规格
价格(RMB)
库存
| 产品名称: | 3-AP |
| CAS No.: | 143621-35-6 |
| Chemical Name: | 2-[(3-amino-2-pyridinyl)methylene]-hydrazinecarbothioamide |
| Synonyms: | PAN-811; NSC# 663249; OCX191 |
| 分子量: | 195.24 |
| 分子式: | C₇H₉N₅S |
| SMILES: | S=C(N)N/N=C/C1=NC=CC=C1N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3-AP (PAN-811) 是一种核糖核苷酸还原酶 (ribonucleotide reductase，RR) 的 M2 亚基抑制剂，是有效的放射致敏剂。 |
| IC50和靶点: | |
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Trondl, R., Flocke, L.S., Kowol, C.R., et al.Triapine and a more potent dimethyl derivative induce ER stress in cancer cellsMol. Pharmacol.85(3),451-459(2013)
