K02288
Cat. No.：YN460014
CAS No. ：1431985-92-0
| 产品名称: | K02288 |
| CAS No.: | 1431985-92-0 |
| Chemical Name: | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]-phenol |
| Synonyms: | K 02288 |
| 分子量: | 352.38 |
| 分子式: | C₂₀H₂₀N₂O₄ |
| SMILES: | OC1=CC=CC(C2=CC(C3=CC(OC)=C(OC)C(OC)=C3)=C(N)N=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | K02288是一种有效的骨形态发生蛋白 (BMP) I型受体抑制剂，抑制ALK1，ALK2，ALK6的IC50为1.8，1.1，6.4 nM。对 ALK3 和 ALK6 的抑制稍弱，IC50在5-34 nM之间。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Brivanlou, A.H., and Darnell, J.E., Jr.Signal transduction and the control of gene expressionScience295(5556),813-818(2002)
Sanvitale, C.E., Kerr, G., Chaikuad, A., et al.A new class of small molecule inhibitor of BMP signalingPLoS One8(4),62721(2013)
