SB-505124
Cat. No.：YN460022
CAS No. ：694433-59-5
| 产品名称: | SB-505124 |
| CAS No.: | 694433-59-5 |
| Chemical Name: | 2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine |
| Synonyms: | SB 505124; SB505124 |
| 分子量: | 335.40 |
| 分子式: | C₂₀H₂₁N₃O₂ |
| SMILES: | CC1=CC=CC(C2=C(C3=CC=C(OCO4)C4=C3)N=C(C(C)(C)C)N2)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB-505124 是一种选择性的TGF-β Receptor type I receptor(ALK4，ALK5，ALK7) 抑制剂，对 LK4，ALK5 的IC50值分别为 129 nM 和 47 nM，对 ALK1，2，3 或 6 无作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
DaCosta Byfield, S., Major, C., Laping, N.J., et al.SB-505124 is a selective inhibitor of transforming growth factor- ß type I receptors ALK4, ALK5, and ALK7Mol. Pharmacol.65(3),744-752(2004)
