ALK-IN-1
Cat. No.:YN440273
| 产品名称: | ALK-IN-1 |
| CAS No.: | 1197958-12-5 |
| Chemical Name: | 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine |
| Synonyms: | Brigatinib analog |
| 分子量: | 529.01 |
| 分子式: | C₂₆H₃₄ClN₆O₂P |
| SMILES: | CP(C)(C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCC(N(C)C)CC4)C=C3OC)=NC=C2Cl)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ALK-IN-1 (Brigatinib analog) 是ALK激酶高效选择性抑制剂,出自专利 US20140066406 A1。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Huang, W.S., Liu, S., Zou, D., et al.Discovery of brigatinib (AP26113), a phosphine oxide-containing, potent, orally active inhibitor of anaplastic lymphoma kinaseJ. Med. Chem.,(2016)