C 87
Cat. No.：YN270015
CAS No. ：332420-90-3
| 产品名称: | C 87 |
| CAS No.: | 332420-90-3 |
| Chemical Name: | 4-[2-(4-chloro-3-nitrophenyl)hydrazone]3-phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione |
| Synonyms: | C87; C-87 |
| 分子量: | 502.93 |
| 分子式: | C₂₄H₁₅ClN₆O₃S |
| SMILES: | O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=CC=C(Cl)C([N+]([O-])=O)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | C87是一种新型小分子TNFα抑制剂; 高效抑制TNFα诱导的细胞毒性，IC50值为8.73 μM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ma, L., Gong, H., Zhu, H., et al.A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse modelJ. Biol. Chem.289(18),12457-12466(2014)
