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N-Formyl-Met-Leu-Phe

Cat. No.:YN270599

  • CAS No. :59880-97-6

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    • 产品名称: N-Formyl-Met-Leu-Phe
      CAS No.: 59880-97-6
      Chemical Name: N-formyl-L-methionyl-L-leucyl-L-phenylalanine
      Synonyms:fMLP; N-Formyl-MLF
      分子量:437.55
      分子式:C₂₁H₃₁N₃O₅S
      SMILES:O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC=O)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) 是一种趋化肽和N-甲酰基肽受体 (FPR) 的特异性配体。报道显示N-Formyl-Met-Leu-Ph 可抑制TNF-alpha的分泌。
      IC50和靶点:
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    • Panaro, M.A., Acquafreddo, A., Sisto, M., et al.Biological role of the N-formyl peptide receptorsImmunopharmacol. Immunotoxicol.28(1),103-127(2006)

      Wang, W., Li, T., Wang, X., et al.FAM19A4 is a novel cytokine ligand of formyl peptide receptor 1 (FPR1) and is able to promote the migration and phagocytosis of macrophagesCell. Mol. Immunol.12(5),615-624(2015)

      Colucci, M., Mastriota, M., Maione, F., et al.Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoidsPeptides32(2),266-271(2011)

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