Calcipotriol monohydrate
Cat. No.：YN470002
CAS No. ：147657-22-5
规格
价格(RMB)
库存
| 产品名称: | Calcipotriol monohydrate |
| CAS No.: | 147657-22-5 |
| Chemical Name: | 24-cyclopropyl-(1α,3β,5Z,7E,22E,24S)-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol, monohydrate |
| Synonyms: | 卡泊三醇一水合物 |
| 分子量: | 430.62 |
| 分子式: | C₂₇H₄₂O₄ |
| SMILES: | O[C@H](C/1=C)C[C@H](O)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](/C=C/[C@@H](O)C4CC4)C)([H])[C@]3(C)CCC\2.O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Calcipotriol是1,25-Dihydroxyvitamin D3类似物，可作用于银屑病。 |
| IC50和靶点: | |
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Kragballe, K.Vitamin D analogues in the treatment of psoriasisJ. Cell. Biochem.49,46-52(1992)
Johansen, C., Kragballe, K., Rasmussen, M., et al.Activator protein 1 DNA binding activity is decreased in lesional psoriatic skin compared with nonlesional psoriatic skinBr. J. Dermatol.151,600-607(2004)
Li, M., Hener, P., Zhang, Z., et al.Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitisProc. Natl. Acad. Sci. USA103(31),11736-11741(2006)
