Paricalcitol
Cat. No.：YN470034
CAS No. ：131918-61-1
规格
价格(RMB)
库存
| 产品名称: | Paricalcitol |
| CAS No.: | 131918-61-1 |
| Chemical Name: | (1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-1,3-cyclohexanediol |
| Synonyms: | 帕立骨化醇 |
| 分子量: | 416.64 |
| 分子式: | C₂₇H₄₄O₃ |
| SMILES: | C[C@]([C@]([C@H](C)/C=C/[C@H](C)C(C)(C)O)([H])CC1)(CCC/2)[C@]1([H])C2=C\C=C3C[C@@H](O)C[C@H](O)C/3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Paricalcitol 是vitamin D receptor的激活剂，用于研究继发性甲状旁腺功能亢进 (分泌过多的甲状旁腺激素)，该疾病与慢性肾功能衰竭有关。 |
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Brown, A.J., Finch, J., Takahashi, F., et al.Calcemic activity of 19-nor-1,25(OH)2D2 decreases with duration of treatmentJ. Am. Soc. Nephrol.11(11),2088-2094(2000)
Donate-Correa, J., Domínguez-Pimentel, V., Muros-de-Fuentes, M., et al.Beneficial effects of selective vitamin D receptor activation by paricalcitol in chronic kidney diseaseCurr. Drug Targets15(7),703-709(2014)
Walf, M., and Thadhani, R.Vitamin D in patients with renal failure: A summary of observational mortality studies and steps moving forwardJ. Steroid Biochem. Mol. Biol.103(3-5),487-490(2007)
Duplancic, D., Cesarik, M., Poljak, N.K., et al.The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protectionClin. Interv. Aging8,149-156(2013)
