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Schisandrin C

Cat. No.:YN251522

  • CAS No. :61301-33-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Schisandrin C
      CAS No.: 61301-33-5
      Chemical Name: (6R,7S,13aS)-5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole
      Synonyms:五味子丙素; Schizandrin-C; Wuweizisu-C
      分子量:384.42
      分子式:C₂₂H₂₄O₆
      SMILES:C[C@H]([C@H](C)C1)CC2=C(C3=C1C=C4OCOC4=C3OC)C(OC)=C5OCOC5=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 五味子丙素(Schisandrin C)是从北五味子木脂素的分离出的天然化合物,在U937细胞中显示有抗癌活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Li, X.Y.Bioactivity of neolignans from fructus SchizandraeMem. Inst. Oswaldo Cruz86 Suppl 2,31-37(1991)

      Park, C., Choi, Y.-W., Hyun, S.K., et al.Induction of G1 arrest and apoptosis by schisandrin C isolated from Schizandra chinensis Baill in human leukemia U937 cellsInt. J. Mol. Med.24(4),495-502(2009)

      Kim, J.S., and Yi, H.K.Schisandrin C enhances mitochondrial biogenesis and autophagy in C2C12 skeletal muscle cells: Potential involvement of anti-oxidative mechanismsNaunyn Schmiedebergs Arch. Pharmacol.391(2),197-206(2018)

      Park, S.Y., Park, S.J., Park, T.G., et al.Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microgliaInt. Immunopharmacol.17(2),415-426(2013)

      Jiang, Y., Fan, X., Wang, Y., et al.Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivationChem. Biol. Interact.231,83-89(2015)

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