CSF1R-IN-2
Cat. No.:YN440147
| 产品名称: | CSF1R-IN-2 |
| CAS No.: | 2271119-26-5 |
| Chemical Name: | (7S)-3-amino-14-ethyl-11-fluoro-4,5,6,7,13,14-hexahydro-7-methyl-4-oxo-1,15-etheno-1H-pyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecine-12-carbonitrile |
| Synonyms: | CSF1R-IN-2 |
| 分子量: | 409.42 |
| 分子式: | C₂₀H₂₀FN₇O₂ |
| SMILES: | N#CC1=C2CN(CC)C(C=C3)=NC(N3N=C4N)=C4C(NC[C@H](C)OC2=CC=C1F)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CSF1R-IN-2 (compound 5) 是SRC,MET和c-FMS的口服有效抑制剂, 其对SRC,MET和c-FMS的IC50值分别为 0.12 nM,0.14 nM 和 0.76 nM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Cui, J.J., Rogers, E.W., Ung, J., et al.Macrocyclic compounds and uses thereof,(2019)