Temsavir
Cat. No.:YN250636
| 产品名称: | Temsavir |
| CAS No.: | 701213-36-7 |
| Chemical Name: | 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-ethanedione |
| Synonyms: | BMS-626529 |
| 分子量: | 473.48 |
| 分子式: | C₂₄H₂₃N₇O₄ |
| SMILES: | O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CNC4=C3C(OC)=CN=C4N5C=NC(C)=N5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Temsavir (BMS-626529) 是一种HIV-1gp120 抑制剂,抑制其结合到 CD4+T 细胞。 |
| IC50和靶点: | |
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Langley, D.R., Kimura, S.R., Sivaprakasam, P., et al.Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of actionProteins83(2),331-350(2015)
Nowicka-Sans, B., Gong, Y.-F., McAuliffe, B., et al.In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068Antimicrob. Agents Chemother.56(7),3498-3507(2012)