Ivabradine hydrochloride
Cat. No.：YN321399
CAS No. ：148849-67-6
规格
价格(RMB)
库存
| 产品名称: | Ivabradine hydrochloride |
| CAS No.: | 148849-67-6 |
| Chemical Name: | 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, monohydrochloride |
| Synonyms: | 盐酸伊伐布雷定 |
| 分子量: | 505.05 |
| 分子式: | C₂₇H₃₇ClN₂O₅ |
| SMILES: | O=C1N(CCCN(C[C@@H]2C3=CC(OC)=C(OC)C=C3C2)C)CCC4=CC(OC)=C(OC)C=C4C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ivabradine hydrochloride 是可口服的，超极化激活的环核苷酸门控离子通道 (HCN) 通道阻滞剂。 |
| IC50和靶点: | |
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Melchiorre, M., Del Lungo, M., Guandalini, L., et al.Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockersJ. Med. Chem.53(18),6773-6777(2010)
Mackiewicz, U., Gerges, J.Y., Chu, S., et al.Ivabradine protects against ventricular arrhythmias in acute myocardial infarction in the ratJ. Cell Physiol.229(6),813-823(2014)
