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Lu AF21934

Cat. No.：1445605-23-1

  • CAS No. ：1445605-23-1

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    • 产品名称: Lu AF21934
      CAS No.: 1445605-23-1
      Chemical Name:
      Synonyms:Lu AF21934;Lu-AF 21934;(1S,2R)-N1-(3,4-dichlorophenyl)cyclohexane-1,2-dicarboxamide;AM80972;(1R,2S)-2-N-(3,4-dichlorophenyl)cyclohexane-1,2-dicarboxamide
      分子量:315.20
      分子式:C₁₄H₁₆Cl₂N₂O₂
      SMILES:O=C([C@@H]1[C@H](C(N)=O)CCCC1)NC2=CC=C(Cl)C(Cl)=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Sławińska, A., Wierońska, J.M., Stachowicz, K., et al.Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective positive allosteric modulator of the mGlu4 receptorNeuropharmacology66,225-235(2013)', 'Sławińska, A., Wierońska, J.M., Stachowicz, K., et al.The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodentsBr. J. Pharmacol.169(8),1824-1839(2013)', 'Ossowska, K., Wardas, J., Berghauzen-Maciejewska, K., et al.Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in ratsNeuropharmacology83,28-35(2014)
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