Eglumegad

Cat. No.：176199-48-7

CAS No. ：176199-48-7

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价格(RMB)

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5mg

￥808

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10mg

￥1140

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50mg

￥4750

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100mg

￥4750

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200mg

￥4750

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产品名称:	Eglumegad
CAS No.:	176199-48-7
Chemical Name:
Synonyms:	LY354740; Eglumetad
分子量:	185.18
分子式:	C₈H₁₁NO₄
SMILES:	OC([C@]1([C@]2([H])[C@@H](C(O)=O)[C@]2([H])CC1)N)=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Rorick-Kehn, L.M., Johnson, B.G., Burkey, J.L., et al.Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic acid (LY404039)J. Pharmacol. Exp. Ther.321(1),308-317(2007)', 'Schoepp, D.D., Johnson, B.G., Wright, R.A., et al.LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptorsNeuropharmacology36(1),1-11(1997)', 'Monn, J.A., Valli, M.J., Massey, S.M., et al.Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): Identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptorsJ. Med. Chem.42(6),1027-1040(1999)', 'Marek, G.J., Wright, R.A., Schoepp, D.D., et al.Physiological antagonism between 5-hydroxytryptamine2A and group II metabotropic glutamate receptors in prefrontal cortexJ. Pharmacol. Exp. Ther.292(1),76-87(2000)', 'Copeland, C.S., Neale, S.A., and Salt, T.E.Actions of xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamusNeuropharmacology66,133-142(2013)', 'Moghaddam, B., and Adams, B.W.Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in ratsScience281(5381),1349-1352(1998)', 'Schoepp, D.D., Jane, D.E., and Monn, J.A.Pharmacological agents acting at subtypes of metabotropic glutamate receptorsNeuropharmacology38(10),1431-1476(1999)