CC214-2
Cat. No.:YN420336
产品名称: | CC214-2 |
CAS No.: | 1246535-95-4 |
Chemical Name: | 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine |
Synonyms: | Desmethyl-SB2343 |
分子量: | 340.38332 |
分子式: | C16H20N8O |
SMILES: | CC(C)N(C=N1)C2=C1C(C3=CN=C(N)N=C3)=NC(N4CCOCC4)=N2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Desmethyl-VS-5584 是 VS-5584 的二甲基类似物,VS-5584 是一种具有吡啶 [2,3-d] 嘧啶结构的有效且有选择性mTOR/PI3K双重抑制剂。 |
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Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11),3238-3250(2014)