Uprosertib hydrochloride
Cat. No.：YN420231
CAS No. ：1047635-80-2
规格
价格(RMB)
库存
| 产品名称: | Uprosertib hydrochloride |
| CAS No.: | 1047635-80-2 |
| Chemical Name: | |
| Synonyms: | GSK2141795 (hydrochloride) |
| 分子量: | 465.71 |
| 分子式: | C₁₈H₁₇Cl₃F₂N₄O₂ |
| SMILES: | O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)O1)N[C@@H](CC3=CC=C(F)C(F)=C3)CN.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Uprosertib hydrochloride (GSK2141795 hydrochloride) 是一种有效的，选择性的Akt广谱抑制剂，抑制 Akt1/Akt2/Akt3 的活性，IC50值分别为 180/328/38 nM。 |
| IC50和靶点: | [{name:"Akt1:180 nM (IC50)"},{name: "Akt2:328 nM (IC50)"},{name: "Akt3:38 nM (IC50)"},{name: "CDK7:2100 nM (IC50)"},{name: "ROCK1:1570 nM (IC50)"},{name: "ROCK2:1850 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
