CHIR 98024
Cat. No.：YN420362
CAS No. ：556813-39-9
规格
价格(RMB)
库存
| 产品名称: | CHIR 98024 |
| CAS No.: | 556813-39-9 |
| Chemical Name: | N6-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine |
| Synonyms: | |
| 分子量: | 486.31384 |
| 分子式: | C20H17Cl2N9O2 |
| SMILES: | NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=C(Cl)C=C(Cl)C=C4)=N2)=CC=C1[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CHIR 98024 (Compound L) 是一种糖原合成酶激酶 3 （GSK3）抑制剂，EC50为 0.2566 μM。 |
| IC50和靶点: | [{name:"GSK-3:0.2566 μM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wagman, A.S., Johnson, K.W., and Bussiere, D.E.Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetesCurr. Pharm. Des.10(10),1105-1137(2004)
