PIK-293
Cat. No.：YN420367
CAS No. ：900185-01-5
| 产品名称: | PIK-293 |
| CAS No.: | 900185-01-5 |
| Chemical Name: | 2-[(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone |
| Synonyms: | PIK-293,PIK293,PIK 293 |
| 分子量: | 397.4 |
| 分子式: | C22H19N7O |
| SMILES: | O=C1N(C(CN2C3=NC=NC(N)=C3C=N2)=NC4=CC=CC(C)=C14)C5=C(C)C=CC=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PIK-293 是 IC87114 的类似物，是PI3K的抑制剂，其对p110δ、p110β、p110γ 和 p110α 的IC50值分别为 0.24 μM、10 μM、25 μM 和100 μM。 |
| IC50和靶点: | [{name:"PI3Kδ:0.24 μM (IC50)"},{name: "PI3Kβ:10 μM (IC50)"},{name: "PI3Kγ:25 μM (IC50)"},{name: "PI3Kα:100 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Knight, Z.A., Gonzalez, B., Feldman, M.E., et al.A pharmacological map of the PI3-K family defines a role for p110α in insulin signalingCell125(4),733-747(2006)
