PHT-427
Cat. No.：YN420109
CAS No. ：1191951-57-1
规格
价格(RMB)
库存
| 产品名称: | PHT-427 |
| CAS No.: | 1191951-57-1 |
| Chemical Name: | 4-dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |
| Synonyms: | CS-0223 |
| 分子量: | 409.61 |
| 分子式: | C₂₀H₃₁N₃O₂S₂ |
| SMILES: | CCCCCCCCCCCCC1=CC=C(C=C1)S(NC2=NN=CS2)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PHT-427 是一种Akt和PDPK1双重抑制剂，与 Akt 和 PDPK1 中的 PH 结构域有亲和性，Ki分别为 2.7 μM 和 5.2 μM。 |
| IC50和靶点: | [{name:"PDPK1:5.2 μM (Ki)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Meuillet, E.J., Zuohe, S., Lemos, R., et al.Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitorMol. Cancer Ther.9(3),706-717(2010)
