O-304
Cat. No.：YN420085
CAS No. ：1261289-04-6
规格
价格(RMB)
库存
| 产品名称: | O-304 |
| CAS No.: | 1261289-04-6 |
| Chemical Name: | 4-chloro-N-[2-[(4-chlorophenyl)methyl]-2,3-dihydro-3-oxo-1,2,4-thiadiazol-5-yl]-benzamide |
| Synonyms: | O-304X |
| 分子量: | 380.25 |
| 分子式: | C₁₆H₁₁Cl₂N₃O₂S |
| SMILES: | O=C(NC(SN1CC2=CC=C(Cl)C=C2)=NC1=O)C3=CC=C(Cl)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | O-304 是一种首创的，具有口服活性的泛AMPK激活剂，可通过抑制 pAMPK 的去磷酸化来增加 AMPK 活性。O-304 可用于 2 型糖尿病和相关心血管并发症的研究。 |
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Steneberg, P., Lindahl, E., Dahl, U., et al.PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes patientsJCI Insight3(12),99114(2018)
