YLF-466D
Cat. No.：YN420227
CAS No. ：1273323-67-3
规格
价格(RMB)
库存
| 产品名称: | YLF-466D |
| CAS No.: | 1273323-67-3 |
| Chemical Name: | 3-[[(3E)-3-[(4-chlorophenyl)phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-1-yl]methyl]-benzoic acid |
| Synonyms: | C24 |
| 分子量: | 465.93 |
| 分子式: | C₂₉H₂₀ClNO₃ |
| SMILES: | O=C(O)C1=CC=CC(CN2C(/C(C3=C2C=CC=C3)=C(C4=CC=C(Cl)C=C4)\C5=CC=CC=C5)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YLF-466D 是一种新型AMPK激活剂，可抑制血小板聚集。 |
| IC50和靶点: | |
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Liu, Y., Park, J.-M., Oh, S.-J., et al.Antiplatelet effect of a newly developed AMP-activated protein kinase activator YLF-466DEur. J. Pharmacol.760,81-87(2015)
Yu, L.-F., Lo, Y.-Y., Su, M.-B., et al.Development of novel alkene oxindole derivatives as orally efficacious AMP-activated protein kinase activatorsACS Med. Chem. Lett.4(5),475-480(2013)
Li, Y.-Y., Yu, L.-F., Zhang, L.-N., et al.Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db miceToxicol. Appl. Pharmacol.273(2),325-334(2013)
