Oligomycin
Cat. No.：YN361006
CAS No. ：1404-19-9
| 产品名称: | Oligomycin |
| CAS No.: | 1404-19-9 |
| Chemical Name: | |
| Synonyms: | 寡霉素 |
| 分子量: | 暂无 |
| 分子式: | 暂无 |
| SMILES: | [Oligomycin] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oligomycin 是一种抗真菌抗生素，是 H+-ATP 合成酶的抑制剂。Oligomycin 断氧化磷酸化和电子传递链。Oligomycin 抑制缺氧性肿瘤细胞HIF-1alpha表达。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Grover, G.J., and Malm, J.Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemiaCardiovasc.Ther.26,287-296(2008)
Salomon, A.R., Voehringer, D.W., Herzenberg, L.A., et al.Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPaseChem. Biol.8,71-80(2001)
Shin, Y.K., Yoo, B.C., Chang, H.J., et al.Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistanceCancer Res.65(8),3162-3170(2005)
Laatsch, H., Kellner, M., Wolf, G., et al.Oligomycin F, a new immunosuppressive homologue of oligomycin AJ. Antibiot. (Tokyo)46(9),1334-1341(1993)
Jackson, J.G., and Thayer, S.A.Mitochondrial modulation of Ca2+-induced Ca2+-release in rat sensory neuronsJ. Neurophysiol.96,1093-1104(2006)
