Oligomycin B
Cat. No.：YN361007
| 产品名称: | Oligomycin B |
| CAS No.: | 11050-94-5 |
| Chemical Name: | (1S,2'R,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,28R,29S)-22-ethyl-5',6'-dihydro-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyra |
| Synonyms: | 寡霉素 B |
| 分子量: | 805.05 |
| 分子式: | C₄₅H₇₂O₁₂ |
| SMILES: | O=C([C@H]([C@@H]([C@H](C([C@](C)([C@@H]([C@H](C/C=C/C=C/[C@]([H])(CC[C@@]1([C@@H]([C@]([H])(O2)[C@H]([C@@]3(O1)C(C[C@H]([C@]([H])(O3)C[C@H](C)O)C)=O)C)C)[H])CC)C)O)O)=O)C)O)C)[C@@H]([C@H]([C@@H](/C=C/C2=O)C)O)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oligomycin B 是一种从链霉菌属中得到的抗生素，为真核生物 ATP 合成酶 (ATP synthase) 抑制剂，可诱导凋亡。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Grover, G.J., and Malm, J.Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemiaCardiovasc.Ther.26,287-296(2008)
Jackson, J.G., and Thayer, S.A.Mitochondrial modulation of Ca2+-induced Ca2+-release in rat sensory neuronsJ. Neurophysiol.96,1093-1104(2006)
