Olmesartan medoxomil
Cat. No.：YN321103
CAS No. ：144689-63-4
| 产品名称: | Olmesartan medoxomil |
| CAS No.: | 144689-63-4 |
| Chemical Name: | 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2’-(2H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester |
| Synonyms: | 奥美沙坦酯; CS 866 |
| 分子量: | 558.59 |
| 分子式: | C₂₉H₃₀N₆O₆ |
| SMILES: | O=C(OCC1=C(OC(O1)=O)C)C2=C(N=C(N2CC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5)CCC)C(O)(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Olmesartan medoxomil 是一种有效的选择性的 血管紧张素 (angiotensin AT1) 受体抑制剂，IC50为 66.2 μM。 |
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Mizuno, M., Sada, T., Ikeda, M., et al.Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonistEur. J. Pharmacol.285(2),181-188(1995)
Okada, K., Hirano, T., Ran, J., et al.Olmesartan medoxomil, an angiotensin II receptor blocker ameliorates insulin resistance and decreases triglyceride production in fructose-fed ratsHypertens. Res.27(4),293-299(2004)
