Benproperine phosphate
Cat. No.：YN300019
| 产品名称: | Benproperine phosphate |
| CAS No.: | 19428-14-9 |
| Chemical Name: | 1-[1-methyl-2-[2-(phenylmethyl)phenoxy]ethyl]-piperidine, monophosphate |
| Synonyms: | Blascorid, Pirexyl phosphate |
| 分子量: | 407.44 |
| 分子式: | C₂₁H₃₀NO₅P |
| SMILES: | CC(N1CCCCC1)COC2=CC=CC=C2CC3=CC=CC=C3.O=P(O)(O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Benproperine phosphate 是一种具有口服活性的，有效的肌动蛋白相关蛋白 2/3 复合亚基 2 (ARPC2) 抑制剂。Benproperine phosphate 通过削弱 Arp2/3 功能来减弱肌动蛋白的聚合反应速率。Benproperine phosphate 有潜力用于止咳，并可以抑制癌细胞迁移和肿瘤转移。 |
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Li, Y., Zhong, D.F., Chen, S.W.C., et al.Identification of some benproperine metabolites in humans and investigation of their antitussive effectActa Pharmacol. Sin.26(12),1519-1526(2005)
Yoon, Y.J., Han, Y.-M., Choi, J., et al.Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasisBiochem. Pharmacol.163,46-59(2019)
