CaMKII-IN-1
Cat. No.：YN380128
CAS No. ：1208123-85-6
| 产品名称: | CaMKII-IN-1 |
| CAS No.: | 1208123-85-6 |
| Chemical Name: | 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-benzenesulfonamide |
| Synonyms: | |
| 分子量: | 548.10 |
| 分子式: | C₂₉H₃₀ClN₅O₂S |
| SMILES: | O=S(C1=CC=CC(Cl)=C1C)(NC2=C(CN(CC3=CC=CC=C3)CC4)C4=NC(NCCC5=CC=CC=C5)=N2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CaMKII-IN-1是CaMKII高效选择性抑制剂，IC50值为63nM,对CaMKIV, MLCK, p38a, Akt1,和PKC几乎无作用。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Asano, S., Komiya, M., Koike, N., et al.5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitorsBioorg. Med. Chem. Lett.20(22),6696-6698(2010)
