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CB1 antagonist 2

Cat. No.：614726-85-1

  • CAS No. ：614726-85-1

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    • 产品名称: CB1 antagonist 2
      CAS No.: 614726-85-1
      Chemical Name:
      Synonyms:AM4113
      分子量:380.66
      分子式:C₁₇H₁₂Cl₃N₃O
      SMILES:O=C(N)C1=NN(C(C2=CC=C(C=C2)Cl)=C1C)C3=CC=C(C=C3Cl)Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Sink, K.S., McLaughlin, P.J., Wood, J.A.T., et al.The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in ratsNeurospsychopharmacology33(4),946-955(2008)', 'Salamone, J.D., McLaughlin, P.J., Sink, K., et al.Cannabinoid CB1 receptor inverse agonists and neutral antagonists: Effects on food intake, food-reinforced behavior and food aversionsPhysiol. Behav.91(4),383-388(2007)', 'Gueye, A.B., Pryslawsky, Y., Trigo, J.M., et al.The CB1 neutral antagonist AM4113 retains the therapeutic efficacy of the inverse agonist rimonabant for nicotine dependence and weight loss with better psychiatric tolerabilityInt. J. Neuropsychopharmacol.,(2016)
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