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AM281

Cat. No.：202463-68-1

  • CAS No. ：202463-68-1

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    • 产品名称: AM281
      CAS No.: 202463-68-1
      Chemical Name:
      Synonyms:1-(2,4-二氯苯基)-5-(4-碘苯基)-4-甲基-N-4-吗啉基-1H-吡唑-3-甲酰胺
      分子量:557.21
      分子式:C₂₁H₁₉Cl₂IN₄O₂
      SMILES:O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCOCC4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Lan, R., Lu, Q., Fan, P., et al.Design and synthesis of the CB1 selective cannabinoid antagonist AM281: A potential human SPECT ligandAAPS Pharmsci.1(3),1-7(1999)', 'Gatley, S.J., Lan, R., Pyatt, B., et al.Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 to rodent brain cannabinoid receptorsLife Sci.61(14),PL-191-PL-197(1997)', 'Jerman, J.C., Gray, J., Brough, S.J., et al.Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptorsBr. J. Anaesth.89(6),882-887(2002)', 'Baker, C.L., and McDougall, J.J.The cannabinomimetic arachidonyl-2-chloroethylamide (ACEA) acts on capsaicin-sensitive TRPV1 receptors but not cannabinoid receptors in rat jointsBr. J. Pharmacol.142(8),1361-1367(2004)', 'Brown, I., Cascio, M.G., Wahle, K.W.J., et al.Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell linesCarcinogenesis31(9),1584-1591(2010)', 'Leterrier, C., Bonnard, D., Carrel, D., et al.Constitutive endocytic cycle of the CB1 cannabinoid receptorJ. Biol. Chem.279(34),36013-36021(2004)
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