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AM251

Cat. No.：183232-66-8

  • CAS No. ：183232-66-8

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    • 产品名称: AM251
      CAS No.: 183232-66-8
      Chemical Name:
      Synonyms:1H-Pyrazole-3-carboxamide,1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-;AM 251;1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide;AM-251;1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidi
      分子量:555.24
      分子式:C₂₂H₂₁Cl₂IN₄O
      SMILES:O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(I)C=C3)=C1C)NN4CCCCC4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Selinsky, B.S., Gupta, K., Sharkey, C.T., et al.Structural analysis of NSAID binding by prostaglandin H2 synthase: Time-dependent and time-independent inhibitors elicit identical enzyme conformationsBiochemistry40(17),5172-5180(2001)', 'Ryberg, E., Larsson, N., Sjögren, S., et al.The orphan receptor GPR55 is a novel cannabinoid receptorBr. J. Pharmacol.152(7),1092-1101(2007)', 'Shearman, L.P., Rosko, K.M., Fleischer, R., et al.Antidepressant-like and anorectic effects of the cannabinoid CB1 receptor inverse agonist AM251 in miceBehav. Pharmacol.14(8),573-582(2003)', 'Baur, R., Gertsch, J., and Sigel, E.The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABAA receptorsBr. J. Pharmacol.165(8),2479-2484(2012)', 'Yoshinaga, T., Uwabe, K., Naito, S., et al.AM251 suppresses epithelial-mesenchymal transition of renal tubular epithelial cellsPloS One11(12),e0167848(2016)', 'Carpi, S., Fogli, S., Romanini, A., et al.AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cellsAnticancer Drugs26(7),754-762(2015)
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