Taranabant
Cat. No.：YN320005
CAS No. ：701977-09-5
规格
价格(RMB)
库存
| 产品名称: | Taranabant |
| CAS No.: | 701977-09-5 |
| Chemical Name: | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]oxy]-propanamide |
| Synonyms: | MK-0364 |
| 分子量: | 515.95 |
| 分子式: | C₂₇H₂₅ClF₃N₃O₂ |
| SMILES: | ClC1=CC=C(C[C@@H](C2=CC=CC(C#N)=C2)[C@@H](NC(C(C)(OC3=CC=C(C=N3)C(F)(F)F)C)=O)C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Taranabant 是一种有效的选择性的cannabinoid 1(CB1) 受体反向激动剂，抑制结合和多种激动剂的功能活性，作用于人 CB1R，Ki为 0.13 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Fong, T.M., Guan, X.-M., Marsh, D.J., et al.Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodentsJ. Pharmacol. Exp. Ther.321(3),1013-1022(2007)
