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2-Arachidonoylglycerol

Cat. No.:YN322103

  • CAS No. :53847-30-6

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    • 参考文献
    • 产品名称: 2-Arachidonoylglycerol
      CAS No.: 53847-30-6
      Chemical Name: 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester
      Synonyms:
      分子量:378.55
      分子式:C₂₃H₃₈O₄
      SMILES:CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC(CO)CO)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 2-Arachidonoylglycerol 是中枢神经系统中的一种内源性大麻素配体。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Stella, N., Schweitzer, P., and Piomelli, D.A second endogenous cannabinoid that modulates long-term potentiationNature388(6644),773-778(1997)

      Sugiura, T., Kodaka, T., Nakane, S., et al.Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compoundsJ. Biol. Chem.274(5),2794-2801(1999)

      Pertwee, R.G.Pharmacology of cannabinoid receptor ligandsCurr. Med. Chem.6(8),635-664(1999)

      Kondo, S., Kondo, H., Nakane, S., et al.2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: Identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca2+-dependent and -independent mechanismsFEBS Lett.429(2),152-156(1998)

      Dinh, T.P., Carpenter, D., Leslie, F.M., et al.Brain monoglyceride lipase participating in endocannabinoid inactivationProc. Natl. Acad. Sci. USA99(16),10819-10824(2002)

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