Pralnacasan
Cat. No.：YN270384
| 产品名称: | Pralnacasan |
| CAS No.: | 192755-52-5 |
| Chemical Name: | |
| Synonyms: | VX-740; HMR 3480 |
| 分子量: | 523.54 |
| 分子式: | C₂₆H₂₉N₅O₇ |
| SMILES: | O=C([C@@H]1CCCN2N1C([C@@H](NC(C3=NC=CC4=C3C=CC=C4)=O)CCC2=O)=O)N[C@@H](C5)[C@H](OCC)OC5=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pralnacasan (VX-740) 是一种有效的，选择性的，非肽型，具有口服活性白介素 1β 转化酶 (ICE, caspase 1) 抑制剂，Ki为 1.4 nM。Pralnacasan 抑制促炎细胞因子IL-18，IL-1β和IFN-γ。Pralnacasan 有潜力用于骨关节炎和类风湿关节炎的研究。 |
| IC50和靶点: | [{name:"Interleukin-1β converting enzyme:1.4 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
