Myrislignan

Cat. No.：YN410110

CAS No. ：171485-39-5

产品名称:	Myrislignan
CAS No.:	171485-39-5
Chemical Name:	αR-[(1S)-1-[2,6-dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxy-benzenemethanol
Synonyms:
分子量:	374.43
分子式:	C₂₁H₂₆O₆
SMILES:	C[C@@H]([C@@H](C1=CC(OC)=C(O)C=C1)O)OC(C(OC)=CC(CC=C)=C2)=C2OC
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

Select Batch:

Purity: 98%

产品描述:	Myrislignan 是从Myristica fragransHoutt 分离得到的一种木酚素，具有抗炎活性。Myrislignan 通过抑制NF-kB信号通路的激活，减轻LPS诱导的小鼠巨噬细胞炎症反应。
IC50和靶点:
In Vitro:
In Vivo:
Clinical Trial:
Solvent & Solubility:

Suwitchayanon, P., Suenaga, K., Iwasaki, A., et al.Myrislignan, a growth inhibitor from the roots of citronella grassNat. Prod. Commun.12(7),1077-1078(2017)
Jin, H., Zhu, Z.-G., Yu, P.-J., et al.Myrislignan attenuates lipopolysaccharide-induced inflammation reaction in murine macrophage cells through inhibition of NF-κB signalling pathway activationPhytother. Res.26(9),1320-1326(2012)
Lu, X., Yang, L., Chen, J., et al.The action and mechanism of myrislignan on A549 cells in vitro and in vivoJ. Nat. Med.71(1),76-85(2017)
Zhang, J., Si, H., Li., B., et al.Myrislignan exhibits activities against Toxoplasma gondii RH strain by triggering mitochondrial dysfunctionFront. Microbiol.10,2152(2019)