BQ-123

Cat. No.：136553-81-6

CAS No. ：136553-81-6

产品名称:	BQ-123
CAS No.:	136553-81-6
Chemical Name:
Synonyms:	BQ123
分子量:	610.70
分子式:	C₃₁H₄₂N₆O₇
SMILES:	O=C(N[C@](C(N(CCC1)[C@]1([H])C2=O)=O)([H])CC(O)=O)[C@H](NC([C@@H](NC([C@H](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Ihara, M., Noguchi, K., Saeki, T., et al.Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptorLife Sci.50(4),247-255(1992)', 'Sakamoto, A., Yanagisawa, M., Sawamura, T., et al.Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonistsJ. Biol. Chem.268(12),8547-8553(1993)', 'Zamora, M.A., Dempsey, E.C., Walchak, S.J., et al.BQ123, an ETA receptor antagonist, inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cellsAm. J. Respir. Cell Mol. Biol.9(4),429-433(1993)', 'Warner, T.D., Allcock, G.H., and Vane, J.R.Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065Br. J. Pharmacol.112(1),207-213(1994)', 'Erdogan, H., Ekici, F., Katar, M., et al.The protective effects of endothelin-A receptor antagonist BQ-123 in pentylenetetrazole-induced seizure in ratsHum. Exp. Toxicol.33(10),1008-1016(2014)