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Ambrisentan

Cat. No.：177036-94-1

  • CAS No. ：177036-94-1

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    • 产品名称: Ambrisentan
      CAS No.: 177036-94-1
      Chemical Name:
      Synonyms:安倍生坦; BSF 208075; LU 208075
      分子量:378.42
      分子式:C₂₂H₂₂N₂O₄
      SMILES:O=C([C@H](C(OC)(C1=CC=CC=C1)C2=CC=CC=C2)OC3=NC(C)=CC(C)=N3)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Yokoyama, Y., Osano, A., Hyashi, H., et al.Endothelin-1 receptors in rat tissues: Characterization by bosentan, ambrisentan and CI-1020Biol. Pharm. Bull.37(3),461-465(2014)', 'Xia, J., Song, J., Zhen, L., et al.Synthesis and in vitro evaluation of ambrisentan analogues as potential endothelin receptor antagonistsBioorg. Med. Chem. Lett.21(13),3894-3897(2011)', 'Angus, J.A., Soeding, P.F., Hughes, R.J.A., et al.Functional estimation of endothelin-1 receptor antagonism by bosentan, macitentan and ambrisentan in human pulmonary and radial arteries in vitroEur. J. Pharmacol.804,111-116(2017)', 'Wagenaar, G.T., Laghmani, e.H., de Visser, Y.P., et al.Ambrisentan reduces pulmonary arterial hypertension but does not stimulate alveolar and vascular development in neonatal rats with hyperoxic lung injuryAm. J. Physiol. Lung Cell Mol. Physiol.304(4),L264-L275(2013)
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