PF-5190457
Cat. No.:YN320614
CAS No. :1334782-79-4
产品名称: | PF-5190457 |
CAS No.: | 1334782-79-4 |
Chemical Name: | 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone |
Synonyms: | PF-05190457 |
分子量: | 512.67 |
分子式: | C₂₉H₃₂N₆OS |
SMILES: | CC1=NC=NC(C2=CC(CC[C@H]3N4CC5(CCN(C(CC6=CN7C=C(C)SC7=N6)=O)CC5)C4)=C3C=C2)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PF-5190457 (PF-05190457) 是一种有效,选择性的生长素释放肽受体 (ghrelin receptor) 反向激动剂,pKi值为 8.36。 |
IC50和靶点: | |
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Bhattacharya, Samit K., et al.: ACS Med. Chem. Let., 5(5), 474-479 (2014)
Ghareeb, Mwlod, et al.: Analy. and Bioanaly. Chem., 407(19), 5603-5613 (2015)