Anamorelin
Cat. No.:YN320901
CAS No. :249921-19-5
产品名称: | Anamorelin |
CAS No.: | 249921-19-5 |
Chemical Name: | (3R)-1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-1,2,2-trimethylhydrazide, 3-piperidinecarboxylic acid |
Synonyms: | RC-1291; ONO-7643 |
分子量: | 546.70 |
分子式: | C₃₁H₄₂N₆O₃ |
SMILES: | [H][C@](CC1=CNC2=CC=CC=C21)(NC(C(C)(C)N)=O)C(N3CCC[C@@](C(N(C)N(C)C)=O)(CC4=CC=CC=C4)C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Anamorelin (RC-1291) 是一种新型ghrelin receptor激动剂,FLIPR 检测中,EC50为 0.74 nM。 |
IC50和靶点: | |
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Morozumi, N., Hanada, T., Habara, H., et al.The role of C-terminal part of ghrelin in pharmacokinetic profile and biological activity in ratsPeptides32(5),1001-1007(2011)
Zhang, H., and Garcia, J.M.Anamorelin hydrochloride for the treatment of cancer-anorexia-cachexia in NSCLCExpert Opin. Pharmacother.16(8),1245-1253(2015)