N-piperidine Ibrutinib hydrochloride
Cat. No.：YN430193
CAS No. ：2231747-18-3
规格
价格(RMB)
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| 产品名称: | N-piperidine Ibrutinib hydrochloride |
| CAS No.: | 2231747-18-3 |
| Chemical Name: | |
| Synonyms: | N-piperidine Ibrutinib (hydrochloride);N-piperidine Ibrutinib hydrochloride |
| 分子量: | 422.91 |
| 分子式: | C₂₂H₂₃ClN₆O |
| SMILES: | NC1=C2C(N(C3CCNCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | N-piperidine Ibrutinib hydrochloride (Compound 1) 是一种可逆的 Ibrutinib 衍生物，N-piperidine Ibrutinib hydrochloride 是一种有效的BTK抑制剂，对 WT BTK 和 C481S BTK 的IC50值分别为 51.0 和 30.7 nM。N-piperidine Ibrutinib hydrochloride 可作为 BTK 配体，用于合成一系列 PROTAC 分子，如 SJF620 (HY-133137)。S |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
