Androgen receptor antagonist 1
Cat. No.：YN430197
CAS No. ：1338812-36-4
规格
价格(RMB)
库存
| 产品名称: | Androgen receptor antagonist 1 |
| CAS No.: | 1338812-36-4 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 416.90 |
| 分子式: | C₂₁H₂₅ClN₄O₃ |
| SMILES: | O=C(C1=CN(CCO)N=C1)N[C@H]2C(C)(C)[C@H](OC3=CC=C(C#N)C(Cl)=C3)C2(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Androgen receptor antagonist 1 是一种口服有效的完整雄激素受体 (AR) 拮抗剂，IC50为 59 nM。Androgen receptor antagonist 1 可用于合成 PROTAC AR 降解剂，1 μM 和 10 μM PROTAC AR 降解剂作用于 LNCaP 细胞，分别导致 24% 和 47% AR 蛋白降解。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
