Cot inhibitor-1
Cat. No.：YN350206
CAS No. ：915365-57-0
| 产品名称: | Cot inhibitor-1 |
| CAS No.: | 915365-57-0 |
| Chemical Name: | |
| Synonyms: | 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]- |
| 分子量: | 553.46 |
| 分子式: | C₂₇H₂₇Cl₂FN₈ |
| SMILES: | N#CC1=C(C2=CC(NCC3=CN(CCN4CCCCCC4)N=N3)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cot inhibitor-1 (compound 28) 是一种选择性的Tpl2 kinase抑制剂，IC50为 28 nM。Cot inhibitor-1 对人全血中 TNF-alpha 的产生具有抑制作用，IC50为 5.7 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
