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Terrein

Cat. No.:YN320526

  • CAS No. :582-46-7

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    • 生物活性
    • 参考文献
    • 产品名称: Terrein
      CAS No.: 582-46-7
      Chemical Name: 4S,5R-dihydroxy-3-(1E)-1-propen-1-yl-2-cyclopenten-1-one
      Synonyms:(+)Terrein; Terrain; NSC 291308; NSC-291308; NSC291308.
      分子量:154.16
      分子式:C₈H₁₀O₃
      SMILES:O=C1C=C(/C=C/C)[C@H](O)[C@H]1O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Terrein 是一种黑色素生成抑制剂。Terrein 诱导乳腺癌细胞凋亡 (apoptosis)。Terrein是铜绿假单胞菌 (Pseudomonas aeruginosa) 中的群体感应和 c-di-GMP 抑制剂。
      IC50和靶点:
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      In Vivo:
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    • Raistrick, H., and Smith, G.Studies in the biochemistry of micro-organisms. The metabolic products of Aspergillus terreus Thom. A new mould metabolic product—terreinBiochem J.29(3),606-611(1935)

      Park, S.H., Kim, D.S., Kim, W.G., et al.Terrein: A new melanogenesis inhibitor and its mechanismCell Mol. Life Sci.61(22),2878-2885(2004)

      Kim, D.S., Cho, H.J., Lee, H.K., et al.Terrein, a fungal metabolite, inhibits the epidermal proliferation of skin equivalentsJ. Dermatol. Sci.46(1),65-68(2007)

      Goutam, J., Sharma, G., Tiwari, V.K., et al.Isolation and characterization of "terrein" an antimicrobial and antitumor compound from endophytic fungus Aspergillus terreus (JAS-2) associated from Achyranthus aspera Varanasi, IndiaFront. Microbiol.8,1334(2017)

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